Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709712 | 0.92 | SLC9A1 (0.56) | SLC9A1SMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL3719608 | 0.89 | SLC9A1 (0.59) | SLC9A1SMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL3713308 | 0.88 | SLC9A1 (0.55) | SLC9A1SMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL3711321 | 0.86 | SLC9A1 (0.55) | SLC9A1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL3714406 | 0.83 | SLC9A1 (0.51) | SLC9A1 | |
| SCHEMBL3720065 | 0.82 | SLC9A1 (0.55) | SLC9A1SMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL3716474 | 0.82 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDS1PR4MEN1 | |
| SCHEMBL3711058 | 0.81 | SLC9A1 (0.53) | SLC9A1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL3711949 | 0.81 | SLC9A1 (0.56) | SLC9A1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3712980 | 0.80 | SLC9A1 (0.56) | SLC9A1SMN1; SMN2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | claimed |
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |