Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 13/20 | 0.55 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709278 | 0.89 | SLC9A1 (0.59) | SLC9A1C3AR1ALDH1A1MEN1POLB | |
| SCHEMBL3711058 | 0.87 | SLC9A1 (0.53) | SLC9A1ALDH1A1MEN1LMNAPOLB | |
| SCHEMBL3715078 | 0.86 | SLC9A1 (0.55) | SLC9A1ALDH1A1MEN1LMNAPOLB | |
| SCHEMBL3719309 | 0.86 | SLC9A1 (0.57) | SLC9A1C3AR1ALDH1A1MEN1MAPT | |
| SCHEMBL3712786 | 0.85 | SLC9A1 (0.54) | SLC9A1C3AR1S1PR4 | |
| SCHEMBL3714406 | 0.83 | SLC9A1 (0.51) | SLC9A1 | |
| SCHEMBL3711949 | 0.83 | SLC9A1 (0.56) | SLC9A1C3AR1ALDH1A1MEN1MAPT | |
| SCHEMBL3720065 | 0.82 | SLC9A1 (0.55) | SLC9A1C3AR1ALDH1A1MEN1LMNA | |
| SCHEMBL3713656 | 0.82 | SLC9A1 (0.55) | SLC9A1C3AR1ALDH1A1MEN1LMNA | |
| SCHEMBL3709712 | 0.81 | SLC9A1 (0.56) | SLC9A1ALDH1A1MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | claimed |
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |