Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716474 | 0.87 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3709712 | 0.85 | SLC9A1 (0.56) | SLC9A1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3719608 | 0.84 | SLC9A1 (0.59) | SLC9A1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3788349 | 0.82 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3713656 | 0.81 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3783985 | 0.81 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDLMNA | |
| SCHEMBL3710904 | 0.80 | SLC9A1 (0.56) | SLC9A1ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL3715078 | 0.80 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3713308 | 0.80 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3719309 | 0.79 | SLC9A1 (0.57) | SLC9A1ALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | claimed |
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |