Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 17/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188575 | 0.88 | NR4A2 (0.48) | OPRK1NR4A2ABL1 | |
| SCHEMBL3711625 | 0.88 | FFAR1 (0.36) | AAK1ABL1 | |
| SCHEMBL3715549 | 0.87 | OPRK1 (0.44) | OPRK1AAK1NR4A2 | |
| SCHEMBL3715130 | 0.87 | OPRK1 (0.45) | OPRK1ABL1OPRM1OPRD1 | |
| SCHEMBL3711387 | 0.81 | AAK1 (0.45) | AAK1NR4A2 | |
| SCHEMBL3717587 | 0.80 | AAK1 (0.42) | AAK1NR4A2 | |
| SCHEMBL3713123 | 0.80 | IKBKE (0.51) | AAK1NR4A2ABL1 | |
| SCHEMBL3715859 | 0.79 | AAK1 (0.44) | AAK1NR4A2 | |
| SCHEMBL3709369 | 0.78 | AAK1 (0.41) | AAK1NR4A2 | |
| SCHEMBL3714045 | 0.77 | CYP19A1 (0.41) | AAK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |