Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716930 | 0.89 | CCNE2 (0.43) | CCNE2CCNE1CDK2GSK3BALDH1A1 | |
| SCHEMBL13188845 | 0.88 | ALDH1A1 (0.51) | OPRK1CCNE2CCNE1CDK2GSK3B | |
| SCHEMBL3713658 | 0.87 | OPRK1 (0.40) | OPRK1NR4A2AAK1 | |
| SCHEMBL3715130 | 0.85 | OPRK1 (0.45) | OPRK1 | |
| SCHEMBL3711387 | 0.81 | AAK1 (0.45) | ALDH1A1KDM4ENR4A2MAPK1CYP11B2 | |
| SCHEMBL3713123 | 0.80 | IKBKE (0.51) | CCNE2CCNE1CDK2GSK3BALDH1A1 | |
| SCHEMBL3717587 | 0.80 | AAK1 (0.42) | ALDH1A1NR4A2MAPK1CYP11B2AAK1 | |
| SCHEMBL3715859 | 0.79 | AAK1 (0.44) | ALDH1A1HSD17B10KDM4ENR4A2CYP11B2 | |
| SCHEMBL3714907 | 0.79 | MAPT (0.50) | OPRK1ALDH1A1 | |
| SCHEMBL3709369 | 0.78 | AAK1 (0.41) | ALDH1A1NR4A2CYP11B2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |