Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.45 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.45 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.45 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.45 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706690 | 0.86 | KDM1A (0.52) | KDM1AGPR119PDE4DPDE4APDE4B | |
| SCHEMBL3718944 | 0.84 | GPR119 (0.42) | GPR119PIM1PIM2 | |
| SCHEMBL3805418 | 0.83 | KDM1A (0.53) | KDM1AGPR119PDE4DPDE4APDE4B | |
| SCHEMBL1632232 | 0.80 | KDM1A (0.50) | KDM1AGPR119PDE4DPDE4APDE4B | |
| SCHEMBL5454387 | 0.78 | GPR119 (0.57) | KDM1AGPR119PDE4DPDE4APDE4B | |
| SCHEMBL3714938 | 0.78 | KDM1A (0.50) | KDM1AGPR119PDE4DPDE4APDE4B | |
| SCHEMBL213729 | 0.76 | KDM1A (0.56) | KDM1AGPR119PDE4DPDE4APDE4B | |
| SCHEMBL1975955 | 0.76 | PIM2 (0.77) | PIM1PIM2 | |
| Hydrochloric Acid SCHEMBL215238 | 0.76 | KDM1A (0.55) | KDM1AGPR119PDE4DPDE4APDE4B | |
| SCHEMBL3711289 | 0.75 | HRH1 (0.52) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |