Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720029 | 0.88 | KDM4E (0.45) | GPR119PIM1PIM2MCHR1JAK2 | |
| SCHEMBL3713722 | 0.84 | KDM1A (0.50) | GPR119PIM1PIM2 | |
| SCHEMBL3714939 | 0.80 | GPR119 (0.46) | GPR119JAK2JAK1TYK2JAK3 | |
| SCHEMBL3717758 | 0.77 | TLR9 (0.47) | GPR119JAK2JAK1PIK3CD | |
| SCHEMBL3711292 | 0.76 | HRH1 (0.51) | — | |
| SCHEMBL14746764 | 0.76 | SCD (0.48) | GPR119 | |
| SCHEMBL3712949 | 0.74 | GPR119 (0.44) | GPR119PIK3CD | |
| SCHEMBL3715196 | 0.74 | GPR119 (0.38) | GPR119JAK2JAK1PIK3CD | |
| SCHEMBL3709889 | 0.74 | GPR119 (0.45) | GPR119 | |
| SCHEMBL3710674 | 0.74 | GPR119 (0.43) | GPR119PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |