Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709887 | 0.86 | GPR119 (0.48) | KDM1ANPBWR1MCHR1GPR119PDE4B | |
| SCHEMBL3805418 | 0.85 | KDM1A (0.53) | KDM1AGPR119PDE4BPDE4APDE4C | |
| SCHEMBL3714939 | 0.83 | GPR119 (0.46) | GPR119PDE4BPIK3CD | |
| SCHEMBL3706690 | 0.82 | KDM1A (0.52) | KDM1AGPR119PDE4BPDE4APDE4C | |
| SCHEMBL1632232 | 0.82 | KDM1A (0.50) | KDM1ANPBWR1MCHR1GPR119PDE4B | |
| SCHEMBL3708948 | 0.80 | GPR119 (0.51) | KDM1AGPR119PDE4BPDE4APDE4C | |
| SCHEMBL3055131 | 0.79 | GPR119 (0.47) | KDM1AGPR119PDE4BPDE4APDE4C | |
| SCHEMBL1149124 | 0.79 | CACNB4 (0.49) | KDM1ANPBWR1MCHR1GPR119PDE4B | |
| SCHEMBL5665583 | 0.78 | KDM1A (0.51) | KDM1ANPBWR1MCHR1GPR119PDE4B | |
| SCHEMBL3717757 | 0.78 | KDM1A (0.51) | KDM1AGPR119PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |