Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803110 | 0.93 | CAPN1 (0.66) | CAPN1CTSS | |
| SCHEMBL2800741 | 0.93 | CAPN1 (0.47) | CAPN1 | |
| SCHEMBL3711942 | 0.82 | CAPN1 (0.87) | CAPN1CTSS | |
| SCHEMBL2802327 | 0.76 | CAPN1 (0.86) | CAPN1CTSS | |
| SCHEMBL2801618 | 0.75 | CAPN1 (0.75) | CAPN1CTSS | |
| SCHEMBL2803091 | 0.74 | ALDH1A1 (0.58) | CAPN1 | |
| SCHEMBL2798791 | 0.74 | CAPN1 (0.61) | CAPN1CTSS | |
| SCHEMBL2800991 | 0.74 | CAPN1 (0.71) | CAPN1CTSS | |
| SCHEMBL2800282 | 0.74 | PYGL (0.47) | CAPN1 | |
| SCHEMBL2800351 | 0.74 | CAPN1 (1.00) | CAPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398783-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | Abbott GmbH & Co. KG (DE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094755-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2010-08-26 | — | — | WO | disclosed |