Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610143 | 0.80 | CA1 (0.48) | SCN5AMAPTSCN1ASCN2ANISCH | |
| SCHEMBL4474937 | 0.79 | LMNA (0.43) | KDM4EMAPTRAB9A | |
| SCHEMBL147828 | 0.78 | CA2 (0.52) | KDM4EMAPTABL1 | |
| SCHEMBL30518373 | 0.77 | NPC1 (0.53) | NPC1RAB9AABL1 | |
| SCHEMBL2560337 | 0.77 | NPC1 (0.53) | NPC1RAB9AABL1 | |
| SCHEMBL3724578 | 0.76 | SCN5A (0.44) | CYP1A2SCN5AKDM4ENPC1ALDH1A1 | |
| SCHEMBL13471699 | 0.76 | CCR1 (0.48) | CYP1A2SCN5AKDM4ENPC1ALDH1A1 | |
| SCHEMBL1416502 | 0.76 | KIF11 (0.51) | CYP1A2SCN5AKDM4ENPC1ALDH1A1 | |
| SCHEMBL1550145 | 0.76 | CHRM5 (0.46) | CYP1A2SCN5AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2559299 | 0.75 | KDM4E (0.45) | CYP1A2SCN5AKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |