Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714035 | 1.00 | PTGS2 (0.57) | PTGS2CA2CA9CA12PTGS1 | |
| SCHEMBL4126119 | 0.83 | AKR1C3 (0.55) | CA2CA9CA12CA1KMT2A | |
| SCHEMBL22558454 | 0.83 | AKR1C3 (0.55) | CA2CA9CA12CA1KMT2A | |
| SCHEMBL3710205 | 0.81 | PTGS2 (0.57) | PTGS2CA2CA9CA12PTGS1 | |
| SCHEMBL3710207 | 0.81 | PTGS2 (0.57) | PTGS2CA2CA9CA12PTGS1 | |
| SCHEMBL10024994 | 0.80 | ALDH1A1 (0.62) | PTGS2CA2CA9CA12PTGS1 | |
| SCHEMBL22366969 | 0.80 | ALDH1A1 (0.62) | PTGS2CA2CA9CA12PTGS1 | |
| SCHEMBL28883389 | 0.80 | ALDH1A1 (0.62) | PTGS2CA2CA9CA12PTGS1 | |
| SCHEMBL10002111 | 0.80 | ALDH1A1 (0.62) | PTGS2CA2CA9CA12PTGS1 | |
| SCHEMBL12416744 | 0.80 | CA2 (0.64) | PTGS2CA2CA9CA12PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097350-A1 | A PROCESS FOR THE PREPARATION OF AN ALDEHYDE BETA-LACTAM COMPOUND | ADAMED SP. Z O.O. (PL) | 2010-09-02 | — | — | WO | disclosed |