Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724775 | 0.88 | EED (0.42) | EEDSUZ12EZH2MAPTMEN1 | |
| SCHEMBL3719582 | 0.78 | WNT3A (0.39) | WNT3ACNR2AOC3EEDSUZ12 | |
| SCHEMBL10010507 | 0.78 | FFAR1 (0.47) | WNT3ACNR2PSEN1PSEN2APH1B | |
| SCHEMBL13047215 | 0.77 | FFAR1 (0.41) | WNT3ACNR2EEDSUZ12EZH2 | |
| SCHEMBL1708599 | 0.76 | WNT3A (0.38) | WNT3ACNR2AOC3EEDSUZ12 | |
| SCHEMBL3722112 | 0.72 | MAPT (0.43) | CYP1A2MAPTCYP2C19MEN1GAA | |
| SCHEMBL10010676 | 0.69 | FFAR1 (0.43) | WNT3AMAPTGAASYK | |
| SCHEMBL10291388 | 0.68 | EED (0.40) | EEDSUZ12EZH2 | |
| SCHEMBL10009384 | 0.67 | FFAR1 (0.45) | EEDSUZ12EZH2 | |
| SCHEMBL10292319 | 0.66 | FFAR1 (0.36) | AOC3EEDSUZ12EZH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |