Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259453 | 0.80 | ALDH1A1 (1.00) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL5096009 | 0.80 | EGLN2 (0.50) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL10490668 | 0.78 | ALDH1A1 (0.62) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL10887539 | 0.77 | ALDH1A1 (0.43) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL864946 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL5151528 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL272835 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL9717697 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ENPP1KDM4EMAPK1LMNA | |
| SCHEMBL609545 | 0.77 | KDM1A (0.44) | ALDH1A1ENPP1MAPK1LMNATSHR | |
| SCHEMBL5164814 | 0.76 | ALDH1A1 (0.65) | ALDH1A1ENPP1KDM4EMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285947-A | Low-temperature curing polyimide precursor solution and preparation method thereof | 北京化工大学常州先进材料研究院 | 2025-01-10 | — | — | CN | claimed |
| EP-0213964-B1 | SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (3) | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-07-31 | — | — | EP | claimed |
| US-4680256-A | Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | claimed |
| EP-0213964-A2 | Silver halide photographic emulsions with novel grain faces (3) | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-03-11 | — | — | EP | claimed |
| CN-119285947-A | Low-temperature curing polyimide precursor solution and preparation method thereof | 北京化工大学常州先进材料研究院 | 2025-01-10 | — | — | CN | disclosed |
| CN-111683951-B | Triazolopyrimidine derivatives useful as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230201205-A1 | TREATING EXTRAPYRAMIDAL SYNDROME USING TRAPIDIL | SINOPIA BIOSCIENCES, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230201205-A1 | TREATING EXTRAPYRAMIDAL SYNDROME USING TRAPIDIL | SINOPIA BIOSCIENCES, INC. | 2023-06-29 | — | — | US | disclosed |
| US-11583532-B2 | Triazolopyrimidine derivatives for use as ghrelin o-acyl transferase (GOAT) inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| US-11583532-B2 | Triazolopyrimidine derivatives for use as ghrelin o-acyl transferase (GOAT) inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| EP-3746443-B1 | TRIAZOLOPYRIMIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2022-07-06 | — | — | EP | disclosed |
| EP-3746443-B1 | TRIAZOLOPYRIMIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2022-07-06 | — | — | EP | disclosed |
| US-20080293713-A1 | Inhibitors of Diacylglycerol O-acyltransferase Type 1 Enzyme | ABBOTT LABORATORIES (US) | 2008-11-27 | — | — | US | disclosed |
| WO-2008132067-A2 | ENZYMATIC METHOD FOR THE PRODUCTION OF MICROCAPSULES | BASF SE (DE) | 2008-11-06 | — | — | WO | disclosed |
| EP-0213964-B1 | SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (3) | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4724200-A | CRYSTAL STRUCTURE | EASTMAN KODAK COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4680255-A | Emulsions and photographic elements containing silver halide grains having tetrahexahedral crystal faces | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| US-4680256-A | Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| US-4680254-A | Emulsions and photographic elements containing silver halide grains having hexoctamedral crystal faces | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0213964-A2 | Silver halide photographic emulsions with novel grain faces (3) | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293713-A1 | Inhibitors of Diacylglycerol O-acyltransferase Type 1 Enzyme | DGAT1, DGAT2, LCAT | ALDH1A1 220/4885ENPP1 270/4885KDM4E 3423/4885 |
| US-20230201205-A1 | TREATING EXTRAPYRAMIDAL SYNDROME USING TRAPIDIL | SLC6A3, PARK7, TAC3 | ALDH1A1 1683/4885ENPP1 154/4885KDM4E 4660/4885 |
| US-11583532-B2 | Triazolopyrimidine derivatives for use as ghrelin o-acyl transferase (GOAT) inhibitors | MBOAT4, GIPR, MTTP | ALDH1A1 407/4885ENPP1 1098/4885KDM4E 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.