Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.61 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GOT1 | P17174 | 7/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712388 | 0.80 | PDGFRB (0.62) | TRPV1P2RX7MEN1KMT2APDGFRB | |
| SCHEMBL17737440 | 0.78 | P2RX7 (0.56) | TRPV1PHGDHP2RX7MEN1KMT2A | |
| SCHEMBL3710143 | 0.78 | SMN1; SMN2 (0.65) | TRPV1MEN1KMT2APOLBRBP4 | |
| SCHEMBL3785601 | 0.77 | TRPV1 (0.72) | TRPV1POLB | |
| SCHEMBL4021355 | 0.77 | TRPV1 (0.69) | TRPV1PHGDHP2RX7KMT2APOLB | |
| SCHEMBL3714314 | 0.77 | TRPV1 (0.60) | TRPV1MEN1KMT2AGOT1POLB | |
| SCHEMBL3716149 | 0.77 | POLB (0.75) | TRPV1MEN1KMT2APOLBRBP4 | |
| SCHEMBL3713332 | 0.77 | MEN1 (0.59) | TRPV1MEN1KMT2AGOT1POLB | |
| SCHEMBL3710250 | 0.76 | NAMPT (0.61) | TRPV1 | |
| SCHEMBL4023952 | 0.75 | TRPV1 (0.69) | TRPV1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092342-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE AS THE MODULATORS OF THE TRPV1 RECEPTOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | WO | disclosed |