Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712718 | 0.77 | KIF18A (0.41) | S1PR4TSHRMAPK1USP7LMNA | |
| SCHEMBL3713750 | 0.76 | TSHR (0.42) | TSHRMAPK1TDP1USP7MAPT | |
| SCHEMBL3717157 | 0.76 | USP7 (0.69) | TSHRMAPK1TDP1PDE7AUSP7 | |
| SCHEMBL3716337 | 0.75 | TSHR (0.41) | S1PR4TSHRMAPK1PDE7AUSP7 | |
| SCHEMBL2681761 | 0.73 | USP7 (0.60) | S1PR4TSHRMAPK1TDP1USP7 | |
| SCHEMBL3654191 | 0.73 | PDE7A (0.63) | S1PR4TSHRMAPK1TDP1PDE7A | |
| SCHEMBL3714951 | 0.73 | VCAM1 (0.38) | TSHRMAPK1TDP1USP7LMNA | |
| SCHEMBL4965836 | 0.72 | MAPK1 (0.62) | S1PR4TSHRMAPK1TDP1PDE7A | |
| SCHEMBL2680991 | 0.72 | TDP1 (0.63) | S1PR4TSHRMAPK1TDP1USP7 | |
| SCHEMBL6251002 | 0.71 | TTR (0.62) | S1PR4TSHRMAPK1TDP1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |