Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709357 | 0.87 | ACP1 (0.53) | ACP1TSHRHIF1AEPAS1HDAC1 | |
| SCHEMBL3716223 | 0.86 | ACP1 (0.56) | ACP1TSHRHIF1AEPAS1HDAC1 | |
| SCHEMBL3718122 | 0.85 | MOK (0.48) | HDAC1 | |
| SCHEMBL3711204 | 0.84 | TP53 (0.55) | ACP1TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL3714015 | 0.82 | JAK2 (0.44) | HDAC1 | |
| SCHEMBL13187726 | 0.81 | ALK (0.45) | ALK | |
| SCHEMBL3711837 | 0.81 | ACP1 (0.57) | ACP1TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL3713800 | 0.81 | HDAC1 (0.44) | HDAC1 | |
| SCHEMBL3720519 | 0.81 | JAK1 (0.52) | — | |
| SCHEMBL3716618 | 0.81 | MMP2 (0.48) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |