Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.33 |
| ▸ | PGR | P06401 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714154 | 0.82 | NR3C1 (0.47) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL3682689 | 0.78 | NR3C1 (0.38) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL3953730 | 0.78 | NR3C1 (0.42) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL3814326 | 0.71 | NR3C1 (0.32) | NR3C1CYP3A4 | |
| SCHEMBL13156327 | 0.69 | BRD4 (0.38) | NR3C1CYP3A4 | |
| SCHEMBL3707342 | 0.68 | NR3C1 (0.45) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL23474198 | 0.68 | LOXL2 (0.50) | NR3C1CYP3A4 | |
| SCHEMBL4044986 | 0.68 | NR3C1 (0.45) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL13155017 | 0.67 | CYP1A2 (0.34) | — | |
| SCHEMBL27151020 | 0.67 | RAB9A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203160-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | Bausch & Lomb Incorporated (US) | 2010-07-07 | — | — | EP | disclosed |
| EP-2061444-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | Bausch & Lomb Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2009042377-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | BAUSCH & LOMB INCORPORATED (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008033655-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB INCORPORATED (US) | 2008-03-20 | — | — | WO | disclosed |