SCHEMBL3715464

SCHEMBL3715464

CC(C)(Br)C(=O)OCCC[Si](C)(C)Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4461359 0.93 ACHE (0.32) POLBGAANPSR1
SCHEMBL5573339 0.93 ACHE (0.32) POLBGAANPSR1
SCHEMBL3837815 0.90 CYP4F2 (0.32)
SCHEMBL5091230 0.89 POLB (0.32) POLBGAANPSR1
SCHEMBL2839715 0.87 POLB (0.33) POLBGAANPSR1
SCHEMBL13159077 0.85 ALOX15 (0.35) POLBGAANPSR1
SCHEMBL23731128 0.85 POLB (0.37) POLBGAANPSR1
SCHEMBL15208684 0.82 POLB (0.32) POLBGAANPSR1
SCHEMBL15208621 0.81 ACHE (0.33) POLBGAANPSR1
SCHEMBL15604268 0.81 POLB (0.31) POLBGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010101606-A2 ATOM TRANSFER RADICAL POLYMERIZATION (ATRP) BASED INORGANIC POLYMER STRUCTURES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-09-10 WO claimed
EP-2687548-B1 ORGANIC/INORGANIC COMPOSITE, MANUFACTURING METHOD THEREFOR, ORGANIC/INORGANIC COMPOSITE FILM, MANUFACTURING METHOD THEREFOR, PHOTONIC CRYSTAL, COATING MATERIAL, THERMOPLASTIC COMPOSITION, MICROSTRUCTURE, OPTICAL MATERIAL, ANTIREFLECTION MEMBER, AND OPTICAL LENS ASAHI CHEMICAL IND (JP) 2019-07-31 EP disclosed
US-9359484-B2 Processes for making polyolefin nanocomposites EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-07 US disclosed
US-9359484-B2 Processes for making polyolefin nanocomposites EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-07 US disclosed
US-20150298097-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2015-10-22 US disclosed
US-20150298097-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2015-10-22 US disclosed
US-20150037535-A1 Organic/Inorganic Composite, Manufacturing Method Therefor, Organic/Inorganic Composite Film, Manufacturing Method Therefor, Photonic Crystal, Coating Material, Thermoplastic Composition, Microstructure, Optical Material, Antireflection Member, and Optical Lens ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-02-05 US disclosed
US-20150037535-A1 Organic/Inorganic Composite, Manufacturing Method Therefor, Organic/Inorganic Composite Film, Manufacturing Method Therefor, Photonic Crystal, Coating Material, Thermoplastic Composition, Microstructure, Optical Material, Antireflection Member, and Optical Lens ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-02-05 US disclosed
US-20140336324-A1 PROCESSES FOR MAKING POLYOLEFIN NANOCOMPOSITES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-11-13 US disclosed
US-20140336324-A1 PROCESSES FOR MAKING POLYOLEFIN NANOCOMPOSITES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-11-13 US disclosed
US-6627314-B2 Polymerizing free radically polymerizable (co)monomers in presence of an initiation system; polymerizing one or more second radically polymerizable comonomers on the tethered polymer chain to form an tethered copolymer chain CARNEGIE MELLON UNIVERSITY 2003-09-30 US disclosed
US-20030095943-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-05-22 US disclosed
US-20030012757-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-01-16 US disclosed
US-20020192367-A1 Fabric care compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-12-19 US disclosed
WO-2002087523-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002088293-A1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002087525-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002087522-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
US-20020106513-A1 Preparation of nanocomposite structures by controlled polymerization CARNEGIE MELLON UNIVERSITY 2002-08-08 US disclosed
WO-2002028912-A2 PREPARATION OF NANOCOMPOSITE STRUCTURES BY CONTROLLED POLYMERIZATION CARNEGIE MELLON UNIVERSITY (US) 2002-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030095943-A1 Hair treatment compositions SPTLC3, HACD3, C18orf63 POLB 868/4885GAA 4764/4885NPSR1 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.