Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27836278 | 0.91 | TSHR (0.36) | TSHRTP53ALDH1A1 | |
| SCHEMBL12723334 | 0.79 | ALDH1A1 (0.42) | TSHRLMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL248930 | 0.77 | ALDH1A1 (0.39) | LMNAPOLBUSP2SMN1; SMN2TP53 | |
| SCHEMBL27854272 | 0.76 | HPGD (0.31) | HPGD | |
| SCHEMBL18282347 | 0.74 | TSHR (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL21747400 | 0.74 | LMNA (0.33) | LMNAPOLBUSP2SMN1; SMN2TP53 | |
| SCHEMBL18900660 | 0.74 | TDP1 (0.36) | LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL21747409 | 0.72 | CES2 (0.34) | LMNAPOLBUSP2SMN1; SMN2TP53 | |
| SCHEMBL18979819 | 0.72 | ALDH1A1 (0.41) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21747305 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115869-A1 | PROPOFOL PHOSPHONYL DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS | SEPS PHARMA N.V. (BE) | 2010-10-14 | — | — | WO | claimed |
| CN-102365101-A | Tissue adhesives and sealants comprising polyglycerol aldehydes | DU PONT | 2012-02-29 | — | — | CN | disclosed |
| CN-102361911-A | Polyglycerol aldehydes | DU PONT | 2012-02-22 | — | — | CN | disclosed |
| WO-2010115869-A1 | PROPOFOL PHOSPHONYL DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS | SEPS PHARMA N.V. (BE) | 2010-10-14 | — | — | WO | disclosed |