SCHEMBL371587

SCHEMBL371587

Oc1ccc(-c2ccc(Oc3ccc(-c4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.82
ESR1 P03372 4/20 0.82
MEN1 O00255 1/20 0.82
KMT2A Q03164 1/20 0.82
LTA4H P09960 5/20 0.67
NR1H2 P55055 1/20 0.67
BAX Q07812 1/20 0.67
PARP10 Q53GL7 1/20 0.54
MMP3 P08254 1/20 0.52
BCL2L1 Q07817 1/20 0.52
ABL1 P00519 2/20 0.50
ABCB1 P08183 2/20 0.50
BCR P11274 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663280 1.00 ESR2 (0.82) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL21495883 1.00 ESR2 (0.82) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL9581090 1.00 ESR2 (0.82) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL10611804 1.00 ESR2 (0.82) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL2196668 1.00 ESR2 (0.82) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL14148732 1.00 ESR2 (0.82) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL3175106 0.91 ESR2 (1.00) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL7811939 0.91 ESR2 (1.00) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL249169 0.91 ESR2 (1.00) ESR2ESR1MEN1KMT2ALTA4H
SCHEMBL18198 0.91 ESR2 (1.00) ESR2ESR1MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 702 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024609-B2 Benzoxazine based polyurethane resin composition HUNTSMAN INTERNATIONAL LLC (US) 2024-07-02 US claimed
EP-3837237-B1 METHOD FOR THE PREPARATION OF A CYCLOALIPHATIC DIESTER COVESTRO DEUTSCHLAND AG (DE) 2024-04-24 EP claimed
US-11655202-B2 Process for preparing a cycloaliphatic diester COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2023-05-23 US claimed
US-20220119334-A1 PROCESS FOR PREPARING A CYCLOALIPHATIC DIESTER COVESTRO DEUTSCHLAND AG (DE) 2022-04-21 US claimed
WO-2021122509-A1 METHOD FOR THE PRODUCTION OF A POLYESTER CARBONATE COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-24 WO claimed
EP-3837237-A1 PROCESS FOR PREPARING A CYCLOALIPHATIC DIESTER Covestro Intellectual Property GmbH & Co. KG (DE) 2021-06-23 EP claimed
WO-2020035519-A1 PROCESS FOR PREPARING A CYCLOALIPHATIC DIESTER COVESTRO DEUTSCHLAND AG (DE) 2020-02-20 WO claimed
US-6881815-B2 Method for the preparation poly(etherimide)s GENERAL ELECTRIC COMPANY (US) 2005-04-19 US claimed
EP-1458791-A1 METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S GENERAL ELECTRIC COMPANY (US) 2004-09-22 EP claimed
US-20040063897-A1 Method for the preparation poly(etherimide)s SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2004-04-01 US claimed
WO-2002055582-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed
WO-2002055585-A2 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2002-07-18 WO claimed
WO-2002055583-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed
WO-2002055584-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed
US-6395862-B1 CONTACTING DIARYLOXY COMPOUND WITH DIHYDRIC PHENOL IN THE PRESENCE OF ALKALI METAL TRIAZINE PYRIDYL SULFONATE, CARBOXY OR PHOSPHONATE GENERAL ELECTRIC COMPANY 2002-05-28 US claimed
US-6376640-B1 USING CESIUM POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY 2002-04-23 US claimed
US-6323304-B1 CONTACTING A DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF CATALYST COMPRISED OF ALKALI OR ALKALINE EARTH METAL-TRANSITION METAL FLUORIDE COMPOUND AND IN PRESENCE OF COCATALYST GENERAL ELECTRIC COMPANY 2001-11-27 US claimed
US-6323303-B1 POLYMERIZING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF A RUTHENIUM (II) OR RUTHENIUM (III) COMPOUND OR COMPLEX; OPTIONALLY IN PRESENCE OF A TETRAALKYL AMMONIUM OR TETRAALKYL PHOSPHONIUM SALT GENERAL ELECTRIC COMPANY 2001-11-27 US claimed
US-6303737-B1 POLYCONDENSATION CATALYSTS WHICH ARE SALTS OF CERTAIN PHENANTHROLINE COMPOUNDS; EXCELLENT POLYMERIZATION RATES; REDUCING THE LEVEL OF BRANCHING SIDE REACTION, I.E., FORMATION OF FRIES PRODUCT GENERAL ELECTRIC COMPANY 2001-10-16 US claimed
US-6291631-B1 CONTACTING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE POLYMERIZATION CATALYST UNDER POLYCARBONATE MELT POLYMERIZATION CONDITIONS GENERAL ELECTRIC COMPANY 2001-09-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220119334-A1 PROCESS FOR PREPARING A CYCLOALIPHATIC DIESTER DECR1, DECR2, DHCR7 ESR2 3301/4885ESR1 4030/4885MEN1 1262/4885
US-11655202-B2 Process for preparing a cycloaliphatic diester DECR1, DECR2, DHCR7 ESR2 3301/4885ESR1 4030/4885MEN1 1262/4885
US-20040063897-A1 Method for the preparation poly(etherimide)s FHIT, PBRM1, PMAIP1 ESR2 3128/4885ESR1 1798/4885MEN1 2497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.