Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15438497 | 0.80 | KMT2A (0.42) | PER2CRY2ALDH1A1AOC2BDKRB2 | |
| SCHEMBL3715212 | 0.79 | TSHR (0.46) | PER2CRY2OPRM1OPRL1AOC2 | |
| SCHEMBL3547090 | 0.77 | CACNA1H (0.36) | ALDH1A1OPRM1OPRL1DDR1NPSR1 | |
| SCHEMBL16703117 | 0.71 | PER2 (0.39) | PER2CRY2OPRM1OPRL1AOC2 | |
| SCHEMBL21389132 | 0.71 | PER2 (0.40) | PER2CRY2OPRM1OPRL1AOC2 | |
| SCHEMBL22833746 | 0.69 | TSHR (0.51) | PER2CRY2ALDH1A1OPRM1OPRL1 | |
| SCHEMBL2036528 | 0.68 | TSHR (0.59) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8031383 | 0.67 | PER2 (0.37) | PER2CRY2OPRM1OPRL1AOC2 | |
| SCHEMBL17176024 | 0.66 | ALDH1A1 (0.45) | ALDH1A1OPRM1OPRL1 | |
| SCHEMBL13432030 | 0.64 | PER2 (0.35) | PER2CRY2OPRM1OPRL1AOC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132693-A2 | OLIGOMER-CONTAINING PYRROLIDINE COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2010-11-18 | — | — | WO | disclosed |