Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.37 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648812 | 0.98 | PER2 (0.38) | PER2CRY2BDKRB2OPRM1OPRL1 | |
| SCHEMBL27602897 | 0.86 | OPRM1 (0.45) | PER2CRY2BDKRB2OPRM1OPRL1 | |
| SCHEMBL28465414 | 0.83 | RARB (0.43) | OPRM1OPRL1 | |
| SCHEMBL16703117 | 0.81 | PER2 (0.39) | PER2CRY2OPRM1OPRL1OPRD1 | |
| SCHEMBL21389132 | 0.80 | PER2 (0.40) | PER2CRY2BDKRB2OPRM1OPRL1 | |
| SCHEMBL27743133 | 0.80 | PER2 (0.37) | PER2CRY2OPRM1OPRL1OPRD1 | |
| SCHEMBL18673587 | 0.78 | BDKRB2 (0.39) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL28538166 | 0.78 | BDKRB2 (0.36) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL13432030 | 0.77 | PER2 (0.35) | PER2CRY2OPRM1OPRL1OPRD1 | |
| SCHEMBL8790538 | 0.77 | RAB9A (0.39) | BDKRB2OPRM1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028066-A | FOR DELIVERING HIGHER CONCENTRATIONS OF BIOACTIVE AGENTS TO IMPROVE EFFICACY OF THE BIOACTIVE AGENTS | IMARX PHARMACEUTICAL CORP. (US) | 2000-02-22 | — | — | US | disclosed |
| WO-1998050041-A1 | NOVEL PRODRUGS COMPRISING FLUORINATED AMPHIPHILES | IMARX PHARMACEUTICAL CORP. (US) | 1998-11-12 | — | — | WO | disclosed |