Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11184720 | 0.98 | LMNA (0.70) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL2328960 | 0.89 | LMNA (0.82) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL29941729 | 0.89 | LMNA (0.82) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL11711802 | 0.86 | ALOX15 (0.66) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL768144 | 0.85 | ALOX15 (0.60) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL768145 | 0.85 | ALOX15 (0.60) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL772495 | 0.85 | ALOX15 (0.56) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL11593019 | 0.84 | TSHR (0.61) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL14112094 | 0.84 | LMNA (0.74) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 | |
| Guaifenesin SCHEMBL4321 | 0.84 | CYP1A2 (1.00) | CYP1A2LMNAAGTR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782992-A1 | NOVEL PROCESS FOR THE PREPARATION OF RANOLAZINE | UNICHEM LABORATORIES LIMITED (IN) | 2021-02-24 | — | — | EP | disclosed |
| US-10266507-B2 | Process for the preparation of ranolazine | UNICHEM LABORATORIES LIMITED (IN) | 2019-04-23 | — | — | US | disclosed |
| US-20180044307-A1 | NOVEL PROCESS FOR THE PREPARATION OF RANOLAZINE | UNICHEM LABORATORIES LIMITED (IN) | 2018-02-15 | — | — | US | disclosed |
| US-20180044307-A1 | NOVEL PROCESS FOR THE PREPARATION OF RANOLAZINE | UNICHEM LABORATORIES LIMITED (IN) | 2018-02-15 | — | — | US | disclosed |
| EP-3233814-A2 | NOVEL PROCESS FOR THE PREPARATION OF RANOLAZINE | Unichem Laboratories Limited (IN) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016142819-A2 | NOVEL PROCESS FOR THE PREPARATION OF RANOLAZINE | UNICHEM LABORATORIES LIMITED (IN) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016142819-A2 | NOVEL PROCESS FOR THE PREPARATION OF RANOLAZINE | UNICHEM LABORATORIES LIMITED (IN) | 2016-09-15 | — | — | WO | disclosed |
| CN-102558097-B | Improved method for synthesizing ranolazine | FUREN MEDICINE GROUP | 2014-05-28 | — | — | CN | disclosed |
| WO-2010097805-A1 | A PROCESS FOR THE PREPARATION OF RANOLAZINE | LUPIN LIMITED (IN) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097805-A1 | A PROCESS FOR THE PREPARATION OF RANOLAZINE | LUPIN LIMITED (IN) | 2010-09-02 | — | — | WO | disclosed |
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |
| WO-1994001395-A1 | PRO-DRUG CAPABLE OF RELEASING AN OXAZOLIDINONE AND, IF NEED BE, AN ACETAMIDOPHENOL | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 1994-01-20 | — | — | WO | disclosed |
| EP-0522176-A1 | DIHYDROPYRIDINE COMPOUNDS, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |
| WO-1992013839-A1 | DIHYDROPYRIDINE COMPOUNDS, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-20 | — | — | WO | disclosed |
| EP-0483932-A1 | Process for the preparation of piperazine derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-05-06 | — | — | EP | disclosed |
| EP-0171702-A1 | Benzoxazinone derivatives, preparation and use | BEECHAM GROUP PLC (GB) | 1986-02-19 | — | — | EP | disclosed |
| EP-0004532-B1 | 1-ARYLOXY-3-NITRATOALKYLAMINO-2-PROPANOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | MERCK PATENT GmbH (DE) | 1981-10-14 | — | — | EP | disclosed |
| US-4288452-A | 1-Aryloxy-3-nitratoalkylamino-2-propanols and use as β-receptor blocker | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-08 | — | — | US | disclosed |
| EP-0004532-A1 | 1-Aryloxy-3-nitratoalkylamino-2-propanols, process for their preparation and pharmaceutical compositions | MERCK PATENT GmbH (DE) | 1979-10-17 | — | — | EP | disclosed |
| US-4154837-A | ANTIARRHYTHMIC, ADRENERGIC BLOCKING AGENTS, ANTIANGINOUS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266507-B2 | Process for the preparation of ranolazine | SCN7A, SCN5A, CYP3A7 | CYP1A2 79/4885LMNA 711/4885AGTR1 281/4885 |
| US-20180044307-A1 | NOVEL PROCESS FOR THE PREPARATION OF RANOLAZINE | SCN7A, CYP3A7, SCN5A | CYP1A2 86/4885LMNA 1183/4885AGTR1 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.