Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SDCBP | O00560 | 1/20 | 0.42 |
| ▸ | SDC2 | P34741 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398430 | 0.87 | MAPT (0.56) | MAPTNPSR1L3MBTL1HDAC1RECQL | |
| SCHEMBL1671565 | 0.82 | NR1H4 (0.54) | MAPTNPSR1L3MBTL1HDAC1RECQL | |
| SCHEMBL7652554 | 0.80 | NPC1 (0.58) | MAPTL3MBTL1HDAC1NAMPTGAA | |
| SCHEMBL19553789 | 0.80 | EPHX2 (0.51) | MAPTNPSR1L3MBTL1HDAC1RECQL | |
| SCHEMBL3180689 | 0.79 | L3MBTL1 (0.61) | MAPTNPSR1L3MBTL1HDAC1RECQL | |
| SCHEMBL23462113 | 0.79 | L3MBTL1 (0.54) | MAPTL3MBTL1HDAC1TDP1NAMPT | |
| SCHEMBL6774590 | 0.79 | L3MBTL1 (0.51) | MAPTL3MBTL1HDAC1TDP1NAMPT | |
| SCHEMBL21523879 | 0.79 | NPC1 (0.64) | MAPTNPSR1L3MBTL1HDAC1RECQL | |
| SCHEMBL3608658 | 0.78 | EPHX2 (0.62) | MAPTL3MBTL1HDAC1TDP1NAMPT | |
| SCHEMBL10227120 | 0.78 | FAAH (0.64) | L3MBTL1HDAC1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111353-A1 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111353-A1 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |