Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402927 | 0.81 | TP53 (0.34) | TP53PTGS2PTGS1SLC6A4KCNH2 | |
| SCHEMBL3711750 | 0.79 | HTR2A (0.40) | SLC6A4KCNH2HTR2AALDH1A1GAA | |
| SCHEMBL1742462 | 0.76 | HSPB1 (0.45) | LMNAMAPK1ALDH1A1GAAMAPT | |
| SCHEMBL10192795 | 0.70 | MAPK14 (0.33) | PTGS2PTGS1SLC6A4KCNH2HTR2A | |
| SCHEMBL414346 | 0.69 | HTR2A (0.31) | TP53PTGS2PTGS1SLC6A4KCNH2 | |
| SCHEMBL10195073 | 0.67 | MAPK14 (0.33) | PTGS2PTGS1MTNR1BL3MBTL1 | |
| SCHEMBL10187594 | 0.67 | MAPK14 (0.33) | KCNH2GHSR | |
| SCHEMBL3713558 | 0.66 | CYP1A2 (0.42) | TP53SLC6A4KCNH2HTR2ALMNA | |
| SCHEMBL738356 | 0.66 | GRM2 (0.46) | PTGS2LMNATRPA1ALDH1A1L3MBTL1 | |
| SCHEMBL10195143 | 0.65 | MAPT (0.36) | TP53LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393796-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089211-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |