Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
| ▸ | IL6 | P05231 | 2/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417562 | 0.84 | BACE1 (0.33) | TP53 | |
| SCHEMBL10195048 | 0.79 | MAPK14 (0.32) | MAPK14 | |
| SCHEMBL402927 | 0.71 | TP53 (0.34) | HTR2ASLC6A4KCNH2MAPK14PTGS2 | |
| SCHEMBL414221 | 0.70 | SLC6A4 (0.40) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL2994640 | 0.70 | CYP11B2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL3716646 | 0.69 | TP53 (0.34) | HTR2ASLC6A4KCNH2PTGS2PTGS1 | |
| SCHEMBL16351650 | 0.69 | MAPK14 (0.32) | HTR2ASLC6A4KCNH2MAPK14 | |
| SCHEMBL10195168 | 0.68 | SLC6A4 (0.38) | HTR2ASLC6A4KCNH2MAPK14 | |
| SCHEMBL10195320 | 0.68 | HTR2A (0.35) | HTR2ASLC6A4KCNH2TP53 | |
| SCHEMBL419382 | 0.68 | ALDH1A1 (0.40) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387569-B1 | HERBCIDES | SYNGENTA LTD (GB) | 2016-06-15 | — | — | EP | disclosed |
| US-20140378305-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2014-12-25 | — | — | US | disclosed |
| US-8865623-B2 | Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and method of controlling weeds | SYNGENTA LIMITED (GB) | 2014-10-21 | — | — | US | disclosed |
| US-20120021907-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2387569-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-11-23 | — | — | EP | disclosed |
| WO-2010081755-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378305-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | HTR2A 1192/4885SLC6A4 1501/4885KCNH2 1267/4885 |
| US-20120021907-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | HTR2A 1320/4885SLC6A4 1443/4885KCNH2 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.