Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188303 | 0.88 | HDAC1 (0.40) | ACP1AKT1HDAC1ALK | |
| SCHEMBL3715992 | 0.84 | MAPK1 (0.43) | ACP1L3MBTL1 | |
| SCHEMBL3711316 | 0.83 | ALK (0.40) | ALKL3MBTL1 | |
| SCHEMBL3712000 | 0.83 | MAPK1 (0.36) | ACP1ALKL3MBTL1 | |
| SCHEMBL3709976 | 0.83 | TP53 (0.49) | ACP1ALK | |
| SCHEMBL3710995 | 0.81 | L3MBTL1 (0.39) | ACP1L3MBTL1 | |
| SCHEMBL3721238 | 0.81 | EPHX2 (0.42) | L3MBTL1 | |
| SCHEMBL3715458 | 0.80 | L3MBTL1 (0.37) | ALKL3MBTL1 | |
| SCHEMBL3709357 | 0.80 | ACP1 (0.53) | ACP1HDAC1ALK | |
| SCHEMBL13188445 | 0.78 | HRH3 (0.41) | ACP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |