Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143900 | 0.85 | MAPK1 (0.47) | MAPK1KDM4EL3MBTL1ATMCA12 | |
| SCHEMBL25209840 | 0.84 | GABRG2 (0.36) | MAPK1KDM4EL3MBTL1CA12CA1 | |
| SCHEMBL15527552 | 0.84 | CYP2C19 (0.48) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL25684289 | 0.83 | SMN1; SMN2 (0.36) | MAPK1KDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL10387390 | 0.83 | KDM4E (0.47) | MAPK1KDM4EL3MBTL1POLBALDH1A1 | |
| SCHEMBL21097101 | 0.83 | MAPK1 (0.45) | MAPK1KDM4EL3MBTL1ATMCA12 | |
| SCHEMBL18358176 | 0.83 | MAPK1 (0.45) | MAPK1KDM4EL3MBTL1ATMCA12 | |
| SCHEMBL10387570 | 0.81 | HCAR3 (0.35) | MAPK1KDM4EL3MBTL1POLBMAPT | |
| SCHEMBL19266144 | 0.81 | ATM (0.50) | MAPK1KDM4EL3MBTL1ATMCA12 | |
| SCHEMBL25579669 | 0.81 | JMJD6 (0.40) | L3MBTL1POLBMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |