Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.40 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720433 | 1.00 | SCN7A (0.49) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3720071 | 0.84 | PDE4B (0.49) | SCN7AKCNH2PDE4BPPARGSMN1; SMN2 | |
| SCHEMBL13002435 | 0.82 | SMN1; SMN2 (0.50) | PDE4BSMN1; SMN2MEN1KMT2APDE4D | |
| SCHEMBL3724307 | 0.82 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3717954 | 0.82 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3720067 | 0.82 | PDE4B (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3721868 | 0.82 | PDE4B (0.48) | SCN7AKCNH2PDE4BMEN1KMT2A | |
| SCHEMBL3717955 | 0.81 | SCN7A (0.49) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3724310 | 0.81 | SCN7A (0.49) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3720755 | 0.81 | PDE4B (0.46) | PDE4BPPARGSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |