Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721868 | 0.84 | PDE4B (0.48) | PDE4BSCN9ASCN7AKCNH2MAPT | |
| SCHEMBL3720433 | 0.84 | SCN7A (0.49) | PDE4BSCN7AKCNH2SMN1; SMN2PPARG | |
| SCHEMBL3717034 | 0.84 | SCN7A (0.49) | PDE4BSCN7AKCNH2SMN1; SMN2PPARG | |
| SCHEMBL3720067 | 0.83 | PDE4B (0.46) | PDE4BSCN9ASCN7AKCNH2MAPT | |
| SCHEMBL3720755 | 0.82 | PDE4B (0.46) | PDE4BMAPTSMN1; SMN2PPARGPOLB | |
| SCHEMBL3717633 | 0.82 | PDE4B (0.47) | PDE4BMAPTSMN1; SMN2HPGDPPARG | |
| SCHEMBL3721089 | 0.81 | PDE4B (0.53) | PDE4BSCN9ASCN7AKCNH2BCHE | |
| SCHEMBL3726804 | 0.81 | ACACB (0.49) | — | |
| SCHEMBL3719225 | 0.81 | PDE4B (0.46) | PDE4BSCN9ASCN7AKCNH2MAPT | |
| SCHEMBL3724295 | 0.81 | PDE4B (0.46) | PDE4BMAPTPPARGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |