Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720271 | 0.86 | PDE4B (0.42) | PDE4BALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3717633 | 0.82 | PDE4B (0.47) | PDE4BALDH1A1KMT2AMAPK14CYP2A6 | |
| SCHEMBL3726377 | 0.81 | ACACB (0.40) | — | |
| SCHEMBL3720755 | 0.81 | PDE4B (0.46) | PDE4BALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3717155 | 0.80 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPK14PPARGSMN1; SMN2 | |
| SCHEMBL3726168 | 0.80 | PDE4B (0.41) | PDE4BALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3719225 | 0.80 | PDE4B (0.46) | PDE4BALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3721868 | 0.79 | PDE4B (0.48) | PDE4BALDH1A1KMT2AMEN1MAPK14 | |
| SCHEMBL3726861 | 0.79 | MAPT (0.32) | L3MBTL1MAPK14MAPTHTTLMNA | |
| SCHEMBL3726862 | 0.78 | TSHR (0.36) | KMT2AMEN1MAPK1MAPK14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |