Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713933 | 0.84 | SCN9A (0.44) | IRAK4FFAR1SCN9AGRM5CYP2A6 | |
| SCHEMBL3715057 | 0.82 | GRM5 (0.56) | FFAR1HDAC6HDAC1GRM5CYP2A6 | |
| SCHEMBL3714118 | 0.81 | HDAC6 (0.43) | FFAR1HDAC6HDAC1GRM5CYP2A6 | |
| SCHEMBL3714679 | 0.81 | KMO (0.51) | FFAR1HDAC6HDAC1GRM5CYP2A6 | |
| SCHEMBL3715704 | 0.80 | FFAR1 (0.40) | FFAR1HDAC6HDAC1GRM5CYP2A6 | |
| SCHEMBL3716655 | 0.79 | FFAR1 (0.45) | FFAR1HDAC6HDAC1GRM5CYP2A6 | |
| SCHEMBL3716179 | 0.78 | CAMK2D (0.47) | FFAR1HDAC6HDAC1CYP2C9 | |
| SCHEMBL13188328 | 0.78 | HDAC6 (0.51) | FFAR1HDAC6HDAC1GRM5HIF1A | |
| SCHEMBL400670 | 0.77 | HDAC1 (0.60) | FFAR1HDAC6HDAC1HIF1AEPAS1 | |
| SCHEMBL3714897 | 0.77 | HDAC1 (0.52) | FFAR1HDAC6HDAC1KAT6AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |