Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187782 | 0.87 | HDAC6 (0.46) | FFAR1HDAC6KDM4DHDAC1GRM5 | |
| SCHEMBL3714679 | 0.84 | KMO (0.51) | FFAR1HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL13187685 | 0.84 | HDAC6 (0.57) | HDAC6KDM4DHDAC1HDAC3HDAC2 | |
| SCHEMBL3711202 | 0.84 | ACACB (0.46) | FFAR1GRM5 | |
| SCHEMBL13187767 | 0.81 | HDAC6 (0.59) | HDAC6KDM4DHDAC1HDAC3HDAC2 | |
| SCHEMBL3714897 | 0.81 | HDAC1 (0.52) | FFAR1HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL3713649 | 0.80 | HDAC1 (0.52) | FFAR1HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL3711290 | 0.79 | FFAR1 (0.47) | FFAR1HDAC6KDM4DHDAC1SMPD1 | |
| SCHEMBL3717482 | 0.79 | IRAK4 (0.48) | FFAR1HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL400670 | 0.78 | HDAC1 (0.60) | FFAR1HDAC6HDAC1KDM1AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |