Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLAT | P00750 | 2/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763862 | 0.85 | KMT2A (0.56) | KMT2APARP10F2PLGPLAU | |
| SCHEMBL3720759 | 0.81 | MAPT (0.55) | KMT2APARP10F2PLGPLAU | |
| SCHEMBL13076454 | 0.79 | ACACB (0.59) | — | |
| SCHEMBL103890 | 0.78 | KMT2A (0.70) | KMT2AGLAPARP10TP53MAPT | |
| SCHEMBL4105007 | 0.76 | GLA (0.61) | KMT2AGLAPARP10TP53MAPT | |
| SCHEMBL2723103 | 0.76 | GLA (0.57) | KMT2AGLAPARP10TP53MAPT | |
| SCHEMBL3717506 | 0.75 | PLAU (0.51) | KMT2APARP10F2PLGPLAU | |
| SCHEMBL17631570 | 0.75 | RAB9A (0.48) | KMT2AGLATP53MAPTLMNA | |
| SCHEMBL185920 | 0.74 | ALDH1A1 (0.56) | KMT2AMAPTLMNAALDH1A1KDM4E | |
| SCHEMBL3720618 | 0.74 | GLA (0.43) | KMT2AGLAPARP10TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |