Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076454 | 0.78 | ACACB (0.59) | TDP1 | |
| SCHEMBL2723103 | 0.78 | GLA (0.57) | GLASYKTTBK1TTBK2MAPT | |
| SCHEMBL8284928 | 0.76 | ADRB2 (0.50) | GLAALDH1A1SMN1; SMN2HPGDADRB2 | |
| SCHEMBL14121172 | 0.76 | ADRB2 (0.50) | GLAALDH1A1SMN1; SMN2HPGDADRB2 | |
| SCHEMBL3720620 | 0.75 | ADRA2A (0.41) | GLASYKTTBK1TTBK2MAPT | |
| SCHEMBL184737 | 0.74 | ROCK1 (0.47) | MAPTTP53ALDH1A1HPGDADRB2 | |
| Hydrochloric Acid SCHEMBL14121068 | 0.74 | PARP10 (0.48) | GLAALDH1A1SMN1; SMN2ADRB2KMT2A | |
| SCHEMBL3717485 | 0.74 | KMT2A (0.49) | GLAMAPTTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL3717486 | 0.72 | ADRA2A (0.41) | GLAMAPTTP53SMN1; SMN2ADRB2 | |
| SCHEMBL39108 | 0.71 | ALDH1A1 (0.56) | GLASYKTTBK1TTBK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |