SCHEMBL3717515

SCHEMBL3717515

COC(=O)c1ccc(-c2ccc(C#N)c(C#N)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 0.50
EGFR P00533 1/20 0.50
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
CA12 O43570 3/20 0.47
CA9 Q16790 3/20 0.47
CA14 Q9ULX7 3/20 0.47
TDP1 Q9NUW8 1/20 0.46
CA7 P43166 1/20 0.46
PLAU P00749 1/20 0.44
PTPN1 P18031 1/20 0.44
XDH P47989 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAOB P27338 1/20 0.43
TBK1 Q9UHD2 1/20 0.43
TSHR P16473 1/20 0.43
NAMPT P43490 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8148281 0.86 CA1 (0.52) CA1CA2CA12CA9CA14
SCHEMBL3722137 0.85 EGFR (0.51) ERN1EGFRCA1CA2CA12
SCHEMBL30849990 0.83 EGFR (0.64) ERN1EGFRPLAUPTPN1ALDH1A1
SCHEMBL21083536 0.83 EGFR (0.64) ERN1EGFRPLAUPTPN1ALDH1A1
SCHEMBL4258396 0.81 CA1 (0.50) CA1CA2CA12CA9CA14
Biphenyl Dimethyl Dicarboxylate SCHEMBL2890577 0.80 CA1 (0.67) ERN1EGFRCA1CA2CA12
SCHEMBL7401479 0.80 CA1 (0.53) CA1CA2CA12CA9CA14
SCHEMBL29256171 0.80 CA1 (0.52) CA1CA2CA12CA9CA14
SCHEMBL2051393 0.80 XDH (0.50) XDH
SCHEMBL13063631 0.80 CA1 (0.53) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2700641-A1 Azulenocyanine analogue compounds comprising anchoring group, method of making the same, and their use as dye for dye-sensitized solar cells Solvay SA (BE) 2014-02-26 EP disclosed
WO-2010136178-A1 THE PREPARATION OF A DYE COMPOUND AND A METHOD FOR MAKING THE SAME CORUS UK LIMITED (GB) 2010-12-02 WO disclosed