Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409668 | 0.84 | FFAR1 (0.46) | LOXL2MAOBLMNATDP1ADRB2 | |
| SCHEMBL22651641 | 0.83 | ALDH1A1 (0.51) | ADRB2ADRB1TSHRMMP2MMP3 | |
| SCHEMBL7749771 | 0.81 | MAPT (0.51) | MAOBTDP1TSHRKDM4EMMP2 | |
| SCHEMBL1808357 | 0.81 | TDP1 (0.44) | LMNATDP1ADRB2ADRB1TSHR | |
| SCHEMBL12384285 | 0.80 | MTNR1A (0.58) | LMNAADRB2ADRB1 | |
| SCHEMBL11780675 | 0.78 | ALDH1A1 (0.50) | LMNAADRB2ADRB1TSHRMMP2 | |
| SCHEMBL7045834 | 0.78 | MAPT (0.54) | MAOBLMNACYP1A2MMP2MMP3 | |
| Acetic Acid SCHEMBL3075493 | 0.78 | ACACB (0.51) | MAOBKDM4EACACB | |
| SCHEMBL5380750 | 0.77 | MAOB (0.42) | MAOB | |
| SCHEMBL16379337 | 0.77 | ALDH1A1 (0.50) | MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111353-A1 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111353-A1 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |