Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALPL | P05186 | 10/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265972 | 0.86 | ALPL (0.65) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL3478310 | 0.78 | PGR (0.47) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL14818717 | 0.78 | PTGS1 (0.57) | ALDH1A1TP53TDP1 | |
| SCHEMBL3454061 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL3454118 | 0.78 | KMT2A (0.55) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL3454451 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNATP53TDP1ALPL | |
| SCHEMBL14803891 | 0.76 | PTGS1 (0.52) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL15966091 | 0.76 | PTGS1 (0.56) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL15916656 | 0.76 | KMT2A (0.70) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL3448568 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231660-A1 | IMIDAZO [1,2-A] PYRIDINE COMPOUNDS | Wyeth LLC (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009086123-A1 | IMIDAZO [1,2-A] PYRIDINE COMPOUNDS | WYETH (US) | 2009-07-09 | — | — | WO | disclosed |