Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15092039 | 0.74 | SLC22A2 (0.41) | SLC22A2SLC47A1MAPTEPHX2GRIN2D | |
| SCHEMBL677012 | 0.74 | EPHX2 (0.38) | SLC22A2SLC47A1MAPTEPHX2GRIN2D | |
| SCHEMBL16387224 | 0.74 | SLC22A2 (0.37) | SLC22A2SLC47A1MAPTEPHX2GRIN2D | |
| SCHEMBL5826989 | 0.71 | SLC22A2 (0.48) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL6031488 | 0.65 | — | — | |
| SCHEMBL455611 | 0.63 | SLC22A2 (0.62) | SLC22A2SLC47A1MAPTEPHX2GRIN2D | |
| SCHEMBL138375 | 0.63 | SLC22A2 (0.62) | SLC22A2SLC47A1MAPTEPHX2GRIN2D | |
| SCHEMBL17347043 | 0.60 | EPHX2 (0.37) | SLC22A2SLC47A1MAPTEPHX2GRIN2D | |
| SCHEMBL23744217 | 0.59 | SLC22A2 (0.39) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL18433666 | 0.59 | SLC22A2 (0.39) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010095041-A2 | COMPOSITIONS, METHODS, AND KITS FOR TREATING INFLUENZA VIRAL INFECTIONS | EXCRX (SINGAPORE) PTE.LTD. (SG) | 2010-08-26 | — | — | WO | disclosed |
| EP-1838297-A1 | 1-AMINOCYCLOHEXANE-DERIVATIVES FOR THE TREATMENT OF MULTIPLE SCLEROSIS EMOTIONAL LABILITY AND PSEUDOBULBAR AFFECT | Merz Pharma GmbH & Co. KGaA (DE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006069294-A1 | 1-AMINOCYCLOHEXANE-DERIVATIVES FOR THE TREATMENT OF MULTIPLE SCLEROSIS EMOTIONAL LABILITY AND PSEUDOBULBAR AFFECT | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-06-29 | — | — | WO | disclosed |