Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18433666 | 0.76 | SLC22A2 (0.39) | SLC22A2SLC47A1MAPTNPC1ALDH1A1 | |
| SCHEMBL28416429 | 0.72 | SLC22A2 (0.56) | SLC22A2SLC47A1MAPTNPC1ALDH1A1 | |
| SCHEMBL15299148 | 0.66 | SLC22A2 (0.31) | SLC22A2SLC47A1MAPT | |
| SCHEMBL18433736 | 0.62 | — | — | |
| SCHEMBL20712063 | 0.62 | NPSR1 (0.45) | SLC22A2SLC47A1MAPTNPC1ALDH1A1 | |
| SCHEMBL105533 | 0.60 | SLC22A2 (0.38) | SLC22A2SLC47A1MAPTNPC1ALDH1A1 | |
| SCHEMBL455611 | 0.60 | SLC22A2 (0.62) | SLC22A2SLC47A1MAPTNPC1ALDH1A1 | |
| SCHEMBL138375 | 0.60 | SLC22A2 (0.62) | SLC22A2SLC47A1MAPTNPC1ALDH1A1 | |
| SCHEMBL677940 | 0.60 | SLC22A2 (0.62) | SLC22A2SLC47A1MAPTNPC1ALDH1A1 | |
| SCHEMBL3717552 | 0.59 | SLC22A2 (0.37) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158781-A1 | METHODS FOR PRACTICAL SYNTHESIS OF DEUTERATED AMINO ACIDS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-08-12 | — | — | WO | disclosed |