Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717557 | 1.00 | LMNA (0.50) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL8237102 | 0.84 | GRIN2D (0.64) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL2009040 | 0.84 | GRIN2D (0.64) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL30481109 | 0.84 | GRIN2D (0.64) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL2009041 | 0.84 | GRIN2D (0.64) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL3718733 | 0.80 | ALDH1A1 (0.69) | LMNAL3MBTL1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8692626 | 0.76 | AMY1A (0.59) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL18502970 | 0.76 | AMY1A (0.59) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL8692623 | 0.76 | AMY1A (0.59) | LMNAHPGDHTTL3MBTL1KMT2A | |
| SCHEMBL28157680 | 0.75 | KMT2A (0.47) | LMNAHPGDHTTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |