SCHEMBL3717604

SCHEMBL3717604

C=CC(=O)OOCC(O)COOC(=O)C(=C)C

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3880871 0.90 TSHR (0.47) TSHRALDH1A1HPGD
SCHEMBL31084211 0.82 TSHR (0.37) TSHRALDH1A1
SCHEMBL473649 0.81 TSHR (0.55) TSHRALDH1A1HPGD
Methacrylic Acid SCHEMBL29539526 0.81 TSHR (0.36) TSHR
Methacrylic Acid SCHEMBL8853138 0.81 TSHR (0.36) TSHR
SCHEMBL17670887 0.80 TSHR (0.35) TSHRHPGD
SCHEMBL2035080 0.79 TSHR (0.52) TSHRALDH1A1HPGD
SCHEMBL2927266 0.79 TSHR (0.42) TSHRALDH1A1
Methacrylic Acid SCHEMBL7262804 0.78 TSHR (0.34) TSHR
SCHEMBL702721 0.77 TSHR (0.39) TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7135531-B2 Spherical catalyst for olefin polymerization BASF CATALYSTS LLC (US) 2006-11-14 US claimed
US-20050176900-A1 Spherical catalyst for olefin polymerization ENGELHARD CORPORATION 2005-08-11 US claimed
US-6627584-B2 Unusually high and durable torque capacity in friction tests ETHYL CORPORATION 2003-09-30 US claimed
US-20030153469-A1 Automatic transmission fluid additive comprising reaction product of hydrocarbyl acrylates and dihydrocarbyldithiophosphoric acids AFTON CHEMICAL INTANGIBLES LLC 2003-08-14 US claimed
US-20250109220-A1 Olefin Polymerization Catalyst Comprising Magnesium, Titanium, an Epoxy Compound and an Internal Electron Donor, Such as a 1,2-Phenylene Dibenzoate-Based Compound W. R. GRACE & CO.-CONN. 2025-04-03 US disclosed
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization W. R. GRACE & CO.- CONN. (US) 2025-03-04 US disclosed
EP-4473023-A1 OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND W.R. GRACE & CO.-CONN. (US) 2024-12-11 EP disclosed
CN-118974105-A Olefin polymerization catalyst comprising magnesium, titanium, epoxy compounds and internal electron donors such as compounds based on 1, 2-phenylene dibenzoate 格雷斯公司 2024-11-15 CN disclosed
US-20240174776-A1 SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION W.R. GRACE & CO.-CONN. (US) 2024-05-30 US disclosed
EP-4308615-A1 SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION W. R. Grace & Co.-Conn (US) 2024-01-24 EP disclosed
CN-117355546-A Spherical catalyst component for olefin polymerization 格雷斯公司 2024-01-05 CN disclosed
WO-2023147021-A1 OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND W.R. GRACE & CO.-CONN. (US) 2023-08-03 WO disclosed
US-20050176900-A1 Spherical catalyst for olefin polymerization ENGELHARD CORPORATION 2005-08-11 US disclosed
US-6627584-B2 Unusually high and durable torque capacity in friction tests ETHYL CORPORATION 2003-09-30 US disclosed
US-20030153469-A1 Automatic transmission fluid additive comprising reaction product of hydrocarbyl acrylates and dihydrocarbyldithiophosphoric acids AFTON CHEMICAL INTANGIBLES LLC 2003-08-14 US disclosed
US-6221546-B1 COMPRISING A WATER INSOLUBLE VINYL OR ACRYLIC POLYMER HAVING A TG LESS THAN 25 DEGREES C EASTMAN KODAK COMPANY 2001-04-24 US disclosed
CN-1281159-A Protective layer for image recording material EASTMAN KODAK CO (US) 2001-01-24 CN disclosed
EP-1069472-A1 Coating composition for a protecting layer for gelatin based photographic products containing a 1H-pyrazolo-[1,5-b][1,2,4]-triazole-type magenta coupler EASTMAN KODAK COMPANY (US) 2001-01-17 EP disclosed
EP-1069471-A1 Coating composition for a protecting layer for image recording materials EASTMAN KODAK COMPANY (US) 2001-01-17 EP disclosed
US-6165653-A Protecting layer for gelatin based photographic products containing 1H-pyrazolo[1,5,-b][1,2,4]triazole-type magenta coupler EASTMAN KODAK COMPANY (US) 2000-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization POF1B, PPOX, OGFOD1 TSHR 3339/4885ALDH1A1 3703/4885HPGD 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.