SCHEMBL3880871

SCHEMBL3880871

C=CC(=O)OOCC(O)COC(=O)C(=C)C

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.47
THRB P10828 1/20 0.34
ALDH1A1 P00352 6/20 0.33
HPGD P15428 2/20 0.33
CYP3A4 P08684 2/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3717604 0.90 TSHR (0.38) TSHRALDH1A1HPGD
SCHEMBL36451 0.87 TSHR (0.53) TSHRTHRBALDH1A1HPGDCYP3A4
SCHEMBL23964584 0.87 TSHR (0.53) TSHRTHRBALDH1A1HPGDCYP3A4
SCHEMBL473649 0.85 TSHR (0.55) TSHRTHRBALDH1A1HPGDCYP3A4
SCHEMBL2035080 0.83 TSHR (0.52) TSHRTHRBALDH1A1HPGDCYP3A4
Acrylic Acid SCHEMBL28639653 0.83 TSHR (0.49) TSHRTHRBALDH1A1HPGDCYP3A4
SCHEMBL17947569 0.81 TSHR (0.47) TSHRTHRBALDH1A1HPGDCYP3A4
SCHEMBL94906 0.81 TSHR (0.68) TSHRTHRBALDH1A1HPGDCYP3A4
SCHEMBL13893065 0.80 TSHR (0.53) TSHRTHRBALDH1A1HPGDCYP3A4
SCHEMBL5606160 0.79 TSHR (0.49) TSHRTHRBALDH1A1HPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1604231-B9 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2009-01-07 EP claimed
EP-1604231-B1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2008-07-02 EP claimed
US-12606660-B2 Acrylic rubber composition NOK CORPORATION (JP) 2026-04-21 US disclosed
US-20240228718-A9 DECORATIVE SHEET C.I. TAKIRON CORPORATION (JP) 2024-07-11 US disclosed
CN-115023464-B Acrylic rubber composition NOK株式会社 2024-06-11 CN disclosed
US-20240158548-A1 ETHYLENE-(METH)ACRYLATE-BASED ELASTOMER AND METHOD FOR PRODUCING THE SAME UNIMATEC CO., LTD. (JP) 2024-05-16 US disclosed
US-20240132686-A1 DECORATIVE SHEET CI TAKIRON CORP (JP) 2024-04-25 US disclosed
US-11932644-B2 Carbamate ester compound and acrylic rubber composition containing the same UNIMATEC CO., LTD. (JP) 2024-03-19 US disclosed
CN-117642438-A Fluorine-containing copolymer and surface-modified substrate using same 优迈特株式会社 2024-03-01 CN disclosed
EP-4310109-A1 ETHYLENE-(METH)ACRYLATE ELASTOMER AND MANUFACTURING METHOD THEREFOR Unimatec Co., Ltd. (JP) 2024-01-24 EP disclosed
EP-4310111-A1 ETHYLENE/(METH)ACRYLATE-BASED ELASTOMER AND PRODUCTION METHOD THEREFOR Unimatec Co., Ltd. (JP) 2024-01-24 EP disclosed
EP-1243606-A1 A resin composition for forming a matte-finished surface and a method of forming a matte-finished surface Four Trend, Inc. (US) 2002-09-25 EP disclosed
EP-1231190-A1 Coated optical fiber SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
US-6395393-B1 MULTILAYER; CORE WITH PHOTOCURABLE COVERINGS THE FURUKAWA ELECTRIC CO., LTD. (JP) 2002-05-28 US disclosed
US-20020028287-A1 Manufacture of optical fiber and optical fiber tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-07 US disclosed
EP-1182178-A1 Manufacture of optical fiber and optical fiber tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-02-27 EP disclosed
US-6198867-B1 POLYSILOXANE ENDCAPPED WITH (METH)ACRYL GROUP, AND CONTAINING AROMATIC HYDROCARBON GROUPS ATTACHED TO SILICON ATOMS, AN UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION CATALYST; LOW VISCOSITY, CURES TO A LOW YOUNG'S MODULUS COATING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-03-06 US disclosed
US-6174604-B1 BINDER COMPRISING A RADICAL POLYMERIZABLE OLIGOMER, A RADICAL POLYMERIZABLE MONOMER, A PHOTOPOLYMERIZATION INITIATOR, AND A SILICONE COMPOUND MODIFIED WITH A GROUP CONTAINING A LONG CHAIN ETHYLENE OXIDE-PROPYLENE OXIDE; SUBMARINE CABLES THE FURUKAWA ELECTRIC CO., LTD. (JP) 2001-01-16 US disclosed
EP-1046619-A2 Coated optical fibres and their manufacture SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-10-25 EP disclosed
EP-0970978-A1 Radiation-curable liquid resin composition suitable for coating optical fibers and optical fiber coated therewith SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11932644-B2 Carbamate ester compound and acrylic rubber composition containing the same SUV39H1, NCEH1, SUV39H2 TSHR 3093/4885THRB 3153/4885ALDH1A1 3226/4885
US-12606660-B2 Acrylic rubber composition SMURF2, SMURF1, RPLP0 TSHR 4628/4885THRB 2897/4885ALDH1A1 3794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.