Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3714477 | 0.84 | ALDH1A1 (0.42) | HDAC6SMN1; SMN2KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL3718952 | 0.84 | PARP1 (0.51) | PARP1SMN1; SMN2POLBALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3718969 | 0.84 | PARP1 (0.51) | PARP1SMN1; SMN2KMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL3716765 | 0.83 | ALDH1A1 (0.42) | HDAC8HDAC6SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3716795 | 0.83 | PARP1 (0.55) | PARP1KCNK3SMN1; SMN2KMT2AKCNK9 | |
| SCHEMBL7945534 | 0.81 | CSF1R (0.49) | PARP1KCNK3HDAC8HDAC6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3718811 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3718178 | 0.80 | CA1 (0.40) | SMN1; SMN2MAPTALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3718123 | 0.79 | HDAC6 (0.45) | KCNK3HDAC8HDAC6SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL3717979 | 0.78 | BCAT2 (0.55) | HDAC8HDAC6SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365508-B2 | Aroyl thiourea derivatives | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-06-14 | — | — | US | disclosed |
| EP-2440522-B1 | AROYLTHIOUREA AND ARYLTHIOCARBONYLUREA DERIVATIVES | UNIV DUNDEE (GB) | 2014-11-12 | — | — | EP | disclosed |
| US-20120149778-A1 | COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE | 2012-06-14 | — | — | US | disclosed |
| WO-2010142956-A2 | COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149778-A1 | COMPOUNDS | AR, NR5A1, NAT1 | PARP1 413/4885KCNK3 1516/4885HDAC8 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.