Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815994 | 0.88 | MEN1 (0.51) | KCNK3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL6811291 | 0.87 | ALDH1A1 (0.48) | KCNK3MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL6816596 | 0.87 | KMT2A (0.49) | MEN1KMT2APARP1NPC1TP53 | |
| SCHEMBL6815699 | 0.86 | HDAC6 (0.50) | KCNK3MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6814449 | 0.85 | KMT2A (0.47) | KCNK3MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL6814470 | 0.85 | DDX3X (0.50) | KCNK3MEN1KMT2APARP1SMN1; SMN2 | |
| SCHEMBL6815442 | 0.84 | RAB9A (0.47) | KCNK3MEN1KMT2APARP1SMN1; SMN2 | |
| SCHEMBL6811424 | 0.84 | MEN1 (0.49) | HSP90AA1MEN1KMT2AHSD17B10PARP1 | |
| SCHEMBL7587767 | 0.84 | SIGMAR1 (0.42) | KCNK3MEN1KMT2APARP1HDAC6 | |
| SCHEMBL7594299 | 0.84 | PARP1 (0.46) | MEN1KMT2APARP1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |