Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707910 | 0.88 | CFTR (0.60) | TAS2R14KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3717334 | 0.82 | TAS2R14 (0.48) | TAS2R14KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL20442580 | 0.80 | TAS2R14 (0.54) | TAS2R14KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6141350 | 0.79 | CFTR (0.64) | TAS2R14KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL14670349 | 0.77 | TAS2R14 (0.68) | TAS2R14HPGDMEN1KMT2AMAPT | |
| SCHEMBL4859959 | 0.76 | KDM4E (0.58) | TAS2R14KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL22720171 | 0.76 | TAS2R14 (0.74) | TAS2R14MEN1KMT2AGAAAKR1C3 | |
| SCHEMBL1356666 | 0.74 | GAA (0.68) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL6813056 | 0.74 | TAS2R14 (0.77) | TAS2R14MEN1KMT2AGAAAKR1C3 | |
| SCHEMBL16060789 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |