Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 10/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.67 |
| ▸ | LIPC | P11150 | 1/20 | 0.58 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 3/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813056 | 0.92 | TAS2R14 (0.77) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL4249358 | 0.90 | TAS2R14 (0.69) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL11544911 | 0.88 | MPO (0.68) | TAS2R14AKR1C3AKR1C2LIPCLIPG | |
| SCHEMBL30294480 | 0.85 | TAS2R14 (0.56) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL22852865 | 0.85 | TAS2R14 (0.56) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL6141544 | 0.84 | AKR1C3 (0.82) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL6141543 | 0.84 | AKR1C3 (0.82) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL6141098 | 0.84 | TAS2R14 (0.71) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL6141255 | 0.84 | TAS2R14 (0.61) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 | |
| SCHEMBL6141440 | 0.84 | TAS2R14 (0.71) | TAS2R14AKR1C3AKR1C2AKR1B1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545651-B2 | Diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2026-02-10 | — | — | US | disclosed |
| US-20220227719-A1 | A diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2022-07-21 | — | — | US | disclosed |
| CN-110229114-B | Remove C2-toSymmetric diphenylamine type chiral bisoxazoline ligand and synthetic method and application thereof | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| WO-2020238559-A1 | DE-C2-SYMMETRIC DIPHENYLAMINE-TYPE CHIRAL BISOXAZOLINE LIGAND, SYNTHESIS METHOD THEREFOR AND USE THEREOF | 浙江工业大学 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020238559-A1 | DE-C2-SYMMETRIC DIPHENYLAMINE-TYPE CHIRAL BISOXAZOLINE LIGAND, SYNTHESIS METHOD THEREFOR AND USE THEREOF | 浙江工业大学 | 2020-12-03 | — | — | WO | disclosed |
| CN-110229114-A | Remove C2-symmetric diphenylamine type chiral bisoxazoline ligand and synthetic method and application thereof | 浙江工业大学 | 2019-09-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227719-A1 | A diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | AOC1, AOC2, AOC3 | TAS2R14 4066/4885AKR1C3 306/4885AKR1C2 355/4885 |
| US-12545651-B2 | Diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | AOC2, AOC1, AOC3 | TAS2R14 3532/4885AKR1C3 108/4885AKR1C2 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.