Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410576 | 0.83 | TDP1 (0.37) | TRIM24TRIM33ERN1KDM4EL3MBTL1 | |
| SCHEMBL9782052 | 0.81 | TRIM24 (0.50) | TRIM24TRIM33KMT2AERN1KDM4E | |
| Butadiene SCHEMBL10799164 | 0.80 | TDP1 (0.35) | TRIM24TRIM33ERN1KDM4EL3MBTL1 | |
| SCHEMBL30107073 | 0.78 | TRIM24 (0.47) | TRIM24TRIM33KMT2AERN1KDM4E | |
| SCHEMBL1464976 | 0.77 | KMT2A (0.54) | TRIM24TRIM33KMT2AERN1KDM4E | |
| SCHEMBL29564068 | 0.74 | COMT (0.49) | KMT2AKDM4EMEN1L3MBTL1COMT | |
| SCHEMBL2112972 | 0.74 | COMT (0.49) | KMT2AKDM4EMEN1L3MBTL1COMT | |
| SCHEMBL28502273 | 0.74 | NFE2L2 (0.43) | KDM4ECOMTLMNANFE2L2NAPRT | |
| SCHEMBL7081072 | 0.74 | KDM4E (0.53) | KMT2AERN1KDM4EMEN1L3MBTL1 | |
| SCHEMBL1465505 | 0.73 | NFE2L2 (0.61) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |