Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | COMT | P21964 | 4/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082184 | 0.83 | NAPRT (0.45) | KDM4EALOX12COMTNAPRTALDH1A1 | |
| SCHEMBL8537341 | 0.83 | FTO (0.49) | KDM4EALOX12COMTALDH1A1L3MBTL1 | |
| SCHEMBL2143047 | 0.81 | KDM4E (0.47) | KDM4EALOX12COMTALDH1A1L3MBTL1 | |
| SCHEMBL2112972 | 0.78 | COMT (0.49) | KDM4EALOX12COMTNAPRTALDH1A1 | |
| SCHEMBL29564068 | 0.78 | COMT (0.49) | KDM4EALOX12COMTNAPRTALDH1A1 | |
| SCHEMBL28502273 | 0.78 | NFE2L2 (0.43) | KDM4EALOX12COMTNAPRTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7085595 | 0.77 | NFE2L2 (0.42) | KDM4EALOX12COMTNAPRTSMN1; SMN2 | |
| SCHEMBL1491207 | 0.77 | KMT2A (0.54) | KDM4EALOX12COMTNAPRTALDH1A1 | |
| SCHEMBL4998230 | 0.77 | KDM4E (0.45) | KDM4EALOX12COMTNAPRTALDH1A1 | |
| SCHEMBL5029453 | 0.77 | NFE2L2 (0.42) | KDM4EALOX12COMTNAPRTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048654-B1 | Process for the preparation of chloropyridine sulfonyl chloride | RUETGERS ORGANICS GMBH (DE) | 2003-07-30 | — | — | EP | claimed |
| US-6310214-B1 | FROM HYDROXYPYRIDINESULPHONIC ACIDS COMPRISING PASSING CHLORINE GAS INTO A MIXTURE OF A HYDROXYPYRIDINESULPHONIC ACID AND OF PHOSPHORUS TRICHLORIDE; HEATING; DISTILLATION | RUETGERS ORGANICS GMBH (DE) | 2001-10-30 | — | — | US | claimed |
| EP-1048654-A2 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-02 | — | — | EP | claimed |
| WO-2000063177-A1 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RÜTGERS ORGANICS GMBH (DE) | 2000-10-26 | — | — | WO | claimed |
| WO-1997007100-A1 | PROCESS FOR THE PRODUCTION OF HYDROXYPYRIDINE SULFONIC ACIDS | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | claimed |
| EP-1048654-B1 | Process for the preparation of chloropyridine sulfonyl chloride | RUETGERS ORGANICS GMBH (DE) | 2003-07-30 | — | — | EP | disclosed |
| US-6310214-B1 | FROM HYDROXYPYRIDINESULPHONIC ACIDS COMPRISING PASSING CHLORINE GAS INTO A MIXTURE OF A HYDROXYPYRIDINESULPHONIC ACID AND OF PHOSPHORUS TRICHLORIDE; HEATING; DISTILLATION | RUETGERS ORGANICS GMBH (DE) | 2001-10-30 | — | — | US | disclosed |
| US-6310214-B1 | FROM HYDROXYPYRIDINESULPHONIC ACIDS COMPRISING PASSING CHLORINE GAS INTO A MIXTURE OF A HYDROXYPYRIDINESULPHONIC ACID AND OF PHOSPHORUS TRICHLORIDE; HEATING; DISTILLATION | RUETGERS ORGANICS GMBH (DE) | 2001-10-30 | — | — | US | disclosed |
| WO-2000063177-A8 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RUETGERS ORGANICS GMBH (DE) | 2001-02-22 | — | — | WO | disclosed |
| JP-2000327661-A | PRODUCTION OF CHLORINATED PYRIDINESULFONIC ACID CHLORIDE | RUETGERS ORGANICS GMBH | 2000-11-28 | — | — | JP | disclosed |
| EP-1048654-A3 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |
| EP-1048654-A2 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-02 | — | — | EP | disclosed |
| EP-1048654-A2 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-02 | — | — | EP | disclosed |
| WO-2000063177-A1 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RÜTGERS ORGANICS GMBH (DE) | 2000-10-26 | — | — | WO | disclosed |
| WO-2000063177-A1 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RÜTGERS ORGANICS GMBH (DE) | 2000-10-26 | — | — | WO | disclosed |
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997007100-A1 | PROCESS FOR THE PRODUCTION OF HYDROXYPYRIDINE SULFONIC ACIDS | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |
| WO-1997007100-A1 | PROCESS FOR THE PRODUCTION OF HYDROXYPYRIDINE SULFONIC ACIDS | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |