Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009396 | 0.86 | L3MBTL1 (0.47) | FBP1MAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2672326 | 0.81 | MEN1 (0.47) | — | |
| SCHEMBL3714556 | 0.81 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1GAATSHR | |
| SCHEMBL3718145 | 0.81 | L3MBTL1 (0.49) | MAPTSMN1; SMN2L3MBTL1ALDH1A1GAA | |
| SCHEMBL2673151 | 0.74 | CYP2D6 (0.48) | AKR1C3AKR1C2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL4035943 | 0.74 | MAPT (0.44) | MAPTL3MBTL1 | |
| SCHEMBL2672732 | 0.73 | MEN1 (0.46) | MAPTSMN1; SMN2L3MBTL1ALDH1A1GAA | |
| SCHEMBL11496408 | 0.71 | GRIA2 (0.43) | MAPTSMN1; SMN2ALDH1A1GAATDP1 | |
| SCHEMBL5737042 | 0.70 | KMT2A (0.48) | SMN1; SMN2L3MBTL1ALDH1A1TSHRTDP1 | |
| SCHEMBL335398 | 0.70 | MAPT (0.51) | MAPTTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116270-A1 | EP2/4 AGONISTS | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |